Risorse su Systems Biology

Già da qualche tempo, ormai, anche grazie al sapiente consiglio del mio amico Domenico, mi sono accostato al magnifico mondo della Systems Biology. Non ho mai pensato a questi studi come ad un cambiamento di rotta, bensì, come ad un modo molto più “smart” di approcciarsi al problema dell’indagine e l’interpretazione di dinamiche complesse come quelle che danno luogo alle patologie per cui non esistono ancora piani di trattamento definitivi.
Sto leggendo da qualche settimana il libro di Palsson “Systems Biology: Properties of Reconstructed Networks” e devo dire che mi sta piacendo molto (se non fosse per le tonnellate di nozioni di biochimica che ogni volta devo andare a rivedere!).
Tuttavia, proprio oggi, alla ricerca di nuovo materiale sulle reaction chains ho trovato alcuni link che sto trovando molto utili e che spero possano essere utili anche ai miei lettori!
Ve li riporto di seguito:

WTEC Study on International Research and Development of Systems Biology

Feedback dynamics and cell function – Why systems biology is called Systems Biology

Systems Biology: A Brief Overview

Can a Biologist Fix a Radio? — or, What I Learned while Studying Apoptosis

BOOK – Olaf Wolkenhauer – Systems Biology: Dynamic Pathway Modelling

Bioengineering and Systems Biology

Analyzing the Biology on the System Level – wei tong

Wolkenhauer-Kitano An Introduction to Systems Biology

A reductionist’s systems biology

Biological Networks- The Tinkerer as an Engineer

Simplicity in Cell Biology

Design Principles of Protein Networks

A systems- and signal-oriented approach to intracellular dynamics

An assessment of systems biology – IBM

Analysis and modelling of signal transduction pathways in systems biology

Computational Challenges of Systems Biology

From molecular to modular cell biology

Fundamental issues in Systems Biology – BioEssays

Modularity and Dynamics of Cellular Networks

Molecular Systems Biology and Dynamics – An Introduction for non biologists

Molecular systems biology at the crossroads – to know less about more, or to know more about less

Network Dynamics and Cell Physiology

Network thinking in ecology and evolution

On the complete determination of biological systems

Robustness – A Key to Evolutionary Design

Schrodinger’s Legacy – Systems and Life

Some new directions in control theory inspired by systems biology

Synthesis and Analysis of a Biological System – Tokyo Univ

Systems approaches to understanding cell signaling and gene regulation

Systems Biology – An Interdisciplinary Approach to Solve Complex Bio-Puzzles

Systems Biology – beyond the buzz

Systems Biology – from physiology to gene regulation

Systems Biology – The Big Picture

Systems biology – will it work?

Systems Biology Is Taking Off

Systems biology may work when we learn to understand the parts in terms of the whole

Systems Biology, Integrative Biology, Predictive Biology

The Dynamic Systems Approach to Control and Regulation of IntraCellular Networks

The frontiers and challenges of biodynamics research

The intricate side of systems biology

The long journey to a Systems Biology of neuronal function

The meaning of systems biology

The nature of systems biology

Systems biology: The reincarnation of systems theory applied in biology

The Role of Control and Systems Theory in Systems Biology

Toward Computational Systems Biology

Kitano – Computational systems biology

Biological Robustness

Biological code breaking in the 21st century

Biological context networks – a mosaic view of the interactome

Cell-free synthetic biology – a bottom-up approach to discovery by design

Circuit diagrams for biological networks

Dry work in a wet world – computation in systems biology

Engineering novel life

From systems biology to synthetic biology

Global systems biology, personalized medicine and molecular epidemiology

Integrating scientific cultures

Integrative biology and systems biology

Is there biological research beyond Systems Biology?

Modularizing gene regulation

Physics takes another stab at biological design principles

Synthetic biology – new engineering rules for an emerging discipline

Systemic determinants of gene evolution and function

The gene and the genon concept – a functional and information-theoretic analysis

The intelligent design of evolution

The Personal Genome Project

Top-down versus bottom-up—rediscovering physiology via systems biology

Towards synthesis of a minimal cell

Back to the biology in systems biology: What can we learn from biomolecular networks?

Cell signaling pathways as control modules – Complexity for simplicity

Computational Systems Biology (CSB) – Its future in Europe

Emergent Properties of Networks of Biological Signaling Pathways

Genomes, phylogeny, and evolutionary systems biology

Motifs, Control, and Stability

Multiscale biosystems integration

Reverse Engineering of Biological Complexity

The Complexity of Simplicity

The minimal genome concept

Understanding biology by reverse engineering the control

Life as Complex Systems – Viewpoint from Intra-Inter Dynamics

Feedback control theory and the challenges of postgenomic molecular biology

Molti hanno un’impronta estremamente ingegneristica (mi scuso sin da ora con coloro che troveranno questi articoli troppo tecnici) e devo dire che ho l’impressione che questa è la prima volta che sento di poter dare un contributo unico alla ricerca in questo campo.
Spero di poter approfondire questo concetto tra qualche settimana, quando avrò finito di leggere il libro!

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